Heparin-Induced Thrombocytopenia and COVID-19

Heparin-induced thrombocytopenia (HIT) has not been included as a possible cause of in Coronavirus Disease 2019 (COVID-19) patients. We report case HIT patient with COVID-19 treated heparin. A 78-year-old man was admitted to our hospital for acute respiratory failure and renal due SARS-CoV-2 infection; intensive care unit, one 5000 IU heparin dose (day 0, platelet count 305,000/?L). On day 2, haemoglobin started decrease stopped. 10, 153,000/?L calcium subcutaneously twice daily started. The further decreased, reaching 49,000/?L on 17, the investigated suspected HIT: an IgG specific chemiluminescence test heparin-PF4 antibodies positive femoral DVT found at ultrasound. Argatroban started, increased without any bleeding thrombosis complication. Our experience shows that may develop patients should be among such